Piston pump platforms
for every scale of chromatography.
Four engineered families — analytical, preparative, bioinert, and industrial — sharing a common mechanical and software architecture so you can scale your platform without re-engineering it.
CRS-HP Series
Compact dual-piston analytical pump designed for high-precision HPLC and UHPLC instruments. Parallel-piston architecture with synchronized cam drive minimizes pulsation while sapphire plungers and ceramic check valves resist aggressive mobile phases.
Best for: analytical HPLC, UHPLC, isocratic and binary gradient instruments, micro-LC, on-line SPE.
CRS-FB Series
Mid-flow preparative pump platform for purification chemistry, flash systems, and scale-up workflows. Larger-bore stainless heads, hardened plungers, and an extended-life seal package keep maintenance intervals long even on solvent-heavy duty cycles.
Best for: preparative HPLC, flash chromatography, semi-prep purification, isolation of natural products and APIs.
CRS-MBio Series
Bioinert piston pump family engineered around the realities of protein purification — high-salt buffers, surfactants, and around-the-clock duty. PEEK and titanium flow paths combined with rear-rinsed plunger seals deliver bioinert performance and long seal life even with concentrated NaCl gradients. The series spans three models tailored to low, medium, and high-flow bio workflows.
Available models
0 – 25 ml/min · 25 MPa
High-pressure, low-flow — analytical bioseparation, oligonucleotide chromatography, and small-column FPLC.
0.01 – 100 ml/min · 10 MPa
Classic mid-flow — protein and antibody purification, AAV polishing, plasmid DNA workflows.
0 – 150 ml/min · 5 MPa
Low-pressure, high-flow — buffer delivery, large-scale prep FPLC, vaccine and biologic downstream.
Best for: FPLC, protein and antibody purification, oligonucleotide chromatography, plasmid DNA workflows, vaccine and AAV polishing.
CRS-LP Series
Large-bore reciprocating pump for process-scale chromatography and continuous biomanufacturing. Industrial-grade frame, dual-redundant pressure sensing, and 24/7 duty rating with optional ATEX-compliant motor packages for solvent environments.
Best for: process-scale prep LC, SMB, continuous bioprocessing skids, pilot purification, large-scale natural product isolation.
Pick the platform that fits your envelope.
| Series | Application | Flow range | Max pressure | Flow path | Typical use |
|---|---|---|---|---|---|
| CRS-HP | Analytical / UHPLC | 0.001–10 ml/min | 60 MPa | SS 316L + sapphire | HPLC, UHPLC, micro-LC |
| CRS-FB | Preparative HPLC | 1–300 ml/min | 30 MPa | SS 316L (PEEK opt.) | Prep, flash, semi-prep |
| CRS-MBio 3 models | FPLC / Bio | 0–150 ml/min | up to 25 MPa | PEEK + titanium | Protein, AAV, mAb |
| CRS-LP | Process / Industrial | 10–1000 ml/min | 15 MPa | SS 316L / Hastelloy | Process LC, SMB |
Need a configuration that isn't on this page?
Tell us about your application — flow envelope, pressure, solvent system, footprint. We tailor CRS pump platforms to your instrument.