Analytical HPLC
Sub-µL/min stability and 60 MPa pressure ratings make CRS-HP the workhorse pump behind isocratic, binary, and quaternary analytical HPLC systems used across pharma QC, environmental, and food safety labs.
- Sub-percent retention time RSD
- Compatible with USP <621> methods
- Tight gradient delay volume
UHPLC
Hardened sapphire plungers, redundant check valves, and intelligent compressibility correction enable CRS pumps to drive sub-2µm columns to their full performance envelope.
- Pressures sustained at 60 MPa
- Fast gradient ramp times
- Low delay volume design
FPLC / Protein Purification
Bioinert PEEK and titanium flow paths protect biologics. Continuous rear-rinsed seals prevent salt crystallization, so high-conductivity gradients don't punish your seals.
- USP Class VI material options
- Salt-tolerant seal architecture
- Low-pulsation gradient mixing
Preparative HPLC
From semi-prep purification of natural products to scale-up of API intermediates, the CRS-FB platform delivers reproducible volumetric flow up to 300 ml/min at 30 MPa.
- Extended seal life under solvent load
- Stable flow during fraction collection
- Field-replaceable head assemblies
Flash Chromatography
Rugged dual-piston design, simple maintenance, and a price point that fits flash instrument BOMs — CRS-FB is the right pump for high-throughput purification environments.
- Tolerant of particulate-rich solvents
- Quick prime and self-flush routines
- Compact OEM footprint
SFC & SMB
Specialty chromatography modes demand specialty pumps. CRS supplies CO₂-rated pump heads for SFC and balanced multi-pump configurations for simulated moving bed systems.
- CO₂-compatible head options
- Synchronized multi-pump control
- Closed-loop pressure regulation
Process-scale Bioprocessing
CRS-LP large-bore pumps are integrated into downstream bioprocessing skids, providing reliable buffer and product flow up to 1 L/min with industrial communication protocols.
- 24/7 continuous duty
- EtherCAT, Modbus, OPC-UA
- GMP documentation available
LC-MS Front End
Low-volume, MS-friendly pump configurations with metal-free wetted parts options serve as the front end for high-sensitivity LC-MS/MS systems.
- Metal-free flow path options
- Low carryover, low delay volume
- Cleanly integrates with autosamplers
Continuous Flow Chemistry
Beyond chromatography — CRS piston pumps are deployed as reagent metering pumps in continuous flow synthesis, PET radiochemistry, and process analytics.
- Precise µL/min metering
- Chemically resistant materials
- Closed-loop flow feedback